| HSPMdb Accession No | HSPMDB000895 |
| PMID | 24548239 |
| Target | Hsp70 |
| HSP Name | Hsc70 (HSPA8) and Hsp72 (HSPA1A) |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Cellular activity | Antiproliferative activity |
| Compound Name | 14b |
| IUPAC Name | N-(2-((2-Methoxy-6-(4-methylpiperazin-1-yl)pyridin-3-yl)thio)-pyrimidin-4-yl)cyclopropanecarboxamide |
| SMILES | COc1nc(ccc1Sc2nccc(NC(=O)C3CC3)n2)N4CCN(C)CC4 |
| Class | 2,5-Thiodipyrimidine and 5-(Phenylthio) pyrimidine acrylamide |
| GI50 (µM) | 58.5 |
| Site of Interaction | Nucleotide binding domain (allosteric site) |
| Cellular assay | Alamar Blue viability assay |
| Cellular Model | Kasumi-1 |
| Disease | Cancer |
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