| HSPMdb Accession No | HSPMDB000856 |
| PMID | 24548207 |
| Target | Hsp70 |
| HSP Name | Hsc70 (HSPA8) and Hsp72 (HSPA1A) |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Cellular activity | Antiproliferative activity |
| Compound Name | 17b |
| IUPAC Name | N-(6-Amino-2-((4,6-dimethoxy-2-morpholinopyrimidin-5-yl)thio)pyrimidin-4-yl)acrylamide |
| SMILES | COc1nc(nc(OC)c1Sc2nc(N)cc(NC(=O)C=C)n2)N3CCOCC3 |
| Class | 2,5-Thiodipyrimidine and 5-(Phenylthio) pyrimidine acrylamide |
| GI50 (µM) | 12.5 |
| Site of Interaction | Nucleotide binding domain (allosteric site) |
| Cellular assay | Alamar Blue viability assay |
| Cellular Model | Kasumi-1 |
| Disease | Cancer |
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