| HSPMdb Accession No | HSPMDB000854 |
| PMID | 29953808 |
| Target | Hsp70 |
| HSP Name | Hsc70 (HSPA8) and Hsp72 (HSPA1A) |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Cellular activity | Antiproliferative activity |
| Compound Name | 61 |
| IUPAC Name | 2-((Z)-((E)-3-ethyl-5-(6-ethyl-3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-oxothiazolidin-2-ylidene)methyl)-3-((5-(trifluoromethyl)furan-2-yl)methyl)thiazol-3-ium chloride |
| SMILES | [Cl-].CCN\1C(=O)C(/SC1=C\c2scc[n+]2Cc3oc(cc3)C(F)(F)F)=C4\Sc5cc(CC)ccc5N4C |
| Class | Benzothiazole Rhodacyanines derivative |
| EC50 (µM) | 1.4 |
| Site of Interaction | Nucleotide binding domain (allosteric site) |
| Cellular assay | MTT viability assay |
| Cellular Model | MEF |
| Disease | Cancer |
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