| HSPMdb Accession No | HSPMDB000847 |
| PMID | 29953808 |
| Target | Hsp70 |
| HSP Name | Hsc70 (HSPA8) and Hsp72 (HSPA1A) |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Cellular activity | Antiproliferative activity |
| Compound Name | 54 |
| IUPAC Name | 3-(2-chlorobenzyl)-2-((Z)-((E)-3-ethyl-5-(3-methyl-6-(methylthio)benzo[d]thiazol-2(3H)-ylidene)-4-oxothiazolidin-2-ylidene)methyl)thiazol-3-ium chloride |
| SMILES | [Cl-].CCN1C(=O)C(\S\C1=C/c2scc[n+]2Cc3ccccc3Cl)=C4/Sc5cc(SC)ccc5N4C |
| Class | Benzothiazole Rhodacyanines derivative |
| EC50 (µM) | 0.75 |
| Site of Interaction | Nucleotide binding domain (allosteric site) |
| Cellular assay | MTT viability assay |
| Cellular Model | MEF |
| Disease | Cancer |
Loading Please Wait ...