| HSPMdb Accession No | HSPMDB000841 |
| PMID | 29953808 |
| Target | Hsp70 |
| HSP Name | Hsc70 (HSPA8) and Hsp72 (HSPA1A) |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Cellular activity | Antiproliferative activity |
| Compound Name | 48 |
| IUPAC Name | 2-((Z)-((E)-5-(3,5-dimethylbenzo[d]thiazol-2(3H)-ylidene)-3-ethyl-4-oxothiazolidin-2-ylidene) methyl)-3-(2-(trifluoromethoxy)benzyl)thiazol-3-ium chloride |
| SMILES | [Cl-].CCN\1C(=O)/C(SC1=C\c2scc[n+]2Cc3ccccc3OC(F)(F)F)=C/4Sc5ccc(C)cc5N4C |
| Class | Benzothiazole Rhodacyanines derivative |
| EC50 (µM) | 1.4 |
| Site of Interaction | Nucleotide binding domain (allosteric site) |
| Cellular assay | MTT viability assay |
| Cellular Model | MEF |
| Disease | Cancer |
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