| HSPMdb Accession No | HSPMDB000829 |
| PMID | 29953808 |
| Target | Hsp70 |
| HSP Name | Hsc70 (HSPA8) and Hsp72 (HSPA1A) |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Cellular activity | Antiproliferative activity |
| Compound Name | 50 |
| IUPAC Name | 2-((Z)-((E)-3-ethyl-5-(5-methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-oxothiazolidin-2- ylidene)methyl)-3-(2-(trifluoromethoxy)benzyl)thiazol-3-ium chloride |
| SMILES | [Cl-].CCN\1C(=O)C(/SC1=C\c2scc[n+]2Cc3ccccc3OC(F)(F)F)=C4\Sc5ccc(OC)cc5N4C |
| Class | Benzothiazole Rhodacyanines derivative |
| EC50 (µM) | 0.16 |
| Site of Interaction | Nucleotide binding domain (allosteric site) |
| Cellular assay | MTT viability assay |
| Cellular Model | MDA-MB-231 |
| Disease | Cancer |
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