| HSPMdb Accession No | HSPMDB000784 |
| PMID | 29953808 |
| Target | Hsp70 |
| HSP Name | Hsc70 (HSPA8) and Hsp72 (HSPA1A) |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Cellular activity | Antiproliferative activity |
| Compound Name | 34 |
| IUPAC Name | 3-((2-bromopyridin-3-yl)methyl)-2-((Z)-((E)-5-(6-chloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-ethyl-4-oxothiazolidin-2-ylidene)methyl)thiazol-3-ium chloride |
| SMILES | [Cl-].CCN1C(/S/C(C1=O)=C2/Sc3cc(Cl)ccc3N2C)=C/c4scc[n+]4Cc5cccnc5Br |
| Class | Benzothiazole Rhodacyanines derivative |
| EC50 (µM) | 1.6 |
| Site of Interaction | Nucleotide binding domain (allosteric site) |
| Cellular assay | MTT viability assay |
| Cellular Model | MDA-MB-231 |
| Disease | Cancer |
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