HSPMdb Accession NoHSPMDB000668
PMID27119979
TargetHsp70
HSP NameHsc70 (HSPA8)
OrganismHuman
LocalizationCytosol and nucleus
Enzymatic activityBinding affinity
Compound Name21
IUPAC Name(2R,3R,4S,5R)-2-(6-Amino-8-((3,4-dichlorobenzyl)amino)-9Hpurin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
SMILESNc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc4ccc(Cl)c(Cl)c4)nc12
Class Adenosine derivative
Kd (µM)3.5
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySurface plasmon resonance (SPR)

Structure



HSPMDB000668

21

Physicochemical Properties