HSPMdb Accession No | HSPMDB000668 |
PMID | 27119979 |
Target | Hsp70 |
HSP Name | Hsc70 (HSPA8) |
Organism | Human |
Localization | Cytosol and nucleus |
Enzymatic activity | Binding affinity |
Compound Name | 21 |
IUPAC Name | (2R,3R,4S,5R)-2-(6-Amino-8-((3,4-dichlorobenzyl)amino)-9Hpurin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol |
SMILES | Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc4ccc(Cl)c(Cl)c4)nc12 |
Class | Adenosine derivative |
Kd (µM) | 3.5 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Surface plasmon resonance (SPR) |