HSPMdb Accession No | HSPMDB000662 |
PMID | 27119979 |
Target | Hsp70 |
HSP Name | Hsc70 (HSPA8) |
Organism | Human |
Localization | Cytosol and nucleus |
Enzymatic activity | Binding affinity |
Compound Name | 14 |
IUPAC Name | 4-Amino-6-(benzylamino)-7-((2R,3R,4S,5R)-3,4-dihydroxy-5(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine5-carbonitrile |
SMILES | Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc4ccccc4)c(C#N)c12 |
Class | Adenosine derivative |
Kd (µM) | 2.8 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Surface plasmon resonance (SPR) |