HSPMdb Accession NoHSPMDB000662
PMID27119979
TargetHsp70
HSP NameHsc70 (HSPA8)
OrganismHuman
LocalizationCytosol and nucleus
Enzymatic activityBinding affinity
Compound Name14
IUPAC Name4-Amino-6-(benzylamino)-7-((2R,3R,4S,5R)-3,4-dihydroxy-5(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine5-carbonitrile
SMILESNc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc4ccccc4)c(C#N)c12
Class Adenosine derivative
Kd (µM)2.8
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySurface plasmon resonance (SPR)

Structure



HSPMDB000662

14

Physicochemical Properties