HSPMdb Accession NoHSPMDB000660
PMID27119979
TargetHsp70
HSP NameHsc70 (HSPA8)
OrganismHuman
LocalizationCytosol and nucleus
Enzymatic activityBinding affinity
Compound Name12
IUPAC Name4-Amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-(methylamino)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
SMILESCNc1n([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c3ncnc(N)c3c1C#N
Class Adenosine derivative
Kd (µM)3.3
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySurface plasmon resonance (SPR)

Structure



HSPMDB000660

12

Physicochemical Properties