HSPMdb Accession NoHSPMDB000659
PMID27119979
TargetHsp70
HSP NameHsc70 (HSPA8)
OrganismHuman
LocalizationCytosol and nucleus
Enzymatic activityBinding affinity
Compound Name10
IUPAC Name4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carboxamide
SMILESC1=C(C2=C(N1C3C(C(C(O3)CO)O)O)N=CN=C2N)C(=O)N
Class Adenosine derivative
Kd (µM)3.3
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySurface plasmon resonance (SPR)

Structure



HSPMDB000659

10

Physicochemical Properties