HSPMdb Accession No | HSPMDB000646 |
PMID | 23819499 |
Target | Hsp70 |
HSP Name | DnaK |
Organism | Bacteria |
Localization | Cytosol and membrane |
Enzymatic activity | Binding affinity (ADP-bound DnaK) |
Compound Name | Zafirlukast (Zaf) |
IUPAC Name | cyclopentyl N-[3-[[2-methoxy-4-[(2-methylphenyl)sulfonylcarbamoyl]phenyl]methyl]-1-methylindol-5-yl]carbamate |
SMILES | CC1=CC=CC=C1S(=O)(=O)NC(=O)C2=CC(=C(C=C2)CC3=CN(C4=C3C=C(C=C4)NC(=O)OC5CCCC5)C)OC |
Class | Library assembled at the University of Michigan's Center for Chemical Genomics |
Kd (µM) | 52 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Intrisic Trp fluortescence |