HSPMdb Accession NoHSPMDB000645
PMID21636681
TargetHsp70
HSP NameHsc70 (HSPA8) and Hsp70 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound Name2-phenylethyenesulfonamide (PES)
IUPAC Name2-phenylethynesulfonamide
SMILESC1=CC=C(C=C1)C#CS(=O)(=O)N
GI50 (µM)5
Site of InteractionC-terminal domain
Cellular assayMTT viability assay
Cellular ModelMDA-MB-468
DiseaseCancer

Structure



HSPMDB000645

2-phenylethyenesulfonamide (PES)

Physicochemical Properties