HSPMdb Accession No | HSPMDB000643 |
PMID | 21636681 |
Target | Hsp70 |
HSP Name | Hsc70 (HSPA8) and Hsp70 (HSPA1A) |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | 2-phenylethyenesulfonamide (PES) |
IUPAC Name | 2-phenylethynesulfonamide |
SMILES | C1=CC=C(C=C1)C#CS(=O)(=O)N |
GI50 (µM) | 11 |
Site of Interaction | C-terminal domain |
Cellular assay | MTT viability assay |
Cellular Model | MCF10A |
Disease | Cancer |