HSPMdb Accession NoHSPMDB000622
PMID19694756
TargetHsp70
HSP NameDnaK
OrganismBacteria
LocalizationCytosol and membrane
Cellular activityAntibacterial activity
Compound NameBI-88E3
IUPAC NameN-[(4-methylphenyl)methyl]-5-nitrofuran-2-carboxamide
SMILESCC1=CC=C(CNC(=O)C2=CC=C(O2)[N+]([O-])=O)C=C1
ClassChem Bridge, MayBridge, Life Chemicals and MicroSource, Gaylordsville, CT, USA
Site of InteractionC-terminal domain
Cellular assayBacterial growth inhibition assay (OD based)
MIC/MBC250 uM
Cellular ModelE. coli at 42 C
DiseaseBacterial infection

Structure



HSPMDB000622

BI-88E3

Physicochemical Properties