HSPMdb Accession NoHSPMDB000605
PMID19694756
TargetHsp70
HSP NameDnaK
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityBinding affinity
Compound NameB12
IUPAC NameN-[(2-fluorophenyl)methyl]thiophene-2-carboxamide
SMILESFC1=CC=CC=C1CNC(=O)C1=CC=CS1
ClassChem Bridge, MayBridge, Life Chemicals and MicroSource, Gaylordsville, CT, USA
Kd (µM)64.1
Site of InteractionC-terminal domain
Type of Enzymatic AssayIsothermal Titration Calorimetry (ITC)
DiseaseBacterial infection

Structure



HSPMDB000605

B12

Physicochemical Properties