HSPMdb Accession NoHSPMDB000602
PMID22546203
TargetHsp70
HSP NameHsp70-DnaJ (RRL)
OrganismRabbit
LocalizationCytosol and nucleus
Enzymatic activityInhibition of chaperone activity
Compound Name3
IUPAC Name7-(2-chlorophenyl)-4-(furan-2-yl)-8-oxa-5,6-diazatricyclo[7.4.0.0²,?]trideca-1(9),4,10,12-tetraene
SMILESClC1=C(C=CC=C1)C1OC2=C(C=CC=C2)C2CC(=NN12)C1=CC=CO1
ClassPhenoxy-N-arylacetamide
IC50 (µM)8.8
Type of Enzymatic AssayRefolding assay (luciferase)

Structure



HSPMDB000602

3

Physicochemical Properties