HSPMdb Accession NoHSPMDB000597
PMID18060774
TargetHsp70
HSP NameDnaK
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name6
IUPAC Name3-[(3S)-3-[(3S)-7-amino-3-{4-[4-(4-bromophenyl)-5-(ethoxycarbonyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl]butanamido}heptanamido]-5-phenylpentanamido]propanoic acid
SMILESCCOC(=O)C1=C(C)N(CCCC(=O)N[C@@H](CCCCN)CC(=O)N[C@@H](CCC2=CC=CC=C2)CC(=O)NCCC(O)=O)C(=O)NC1C1=CC=C(Br)C=C1
ClassDihydropyrimidine
EC50 (µM)107
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000597

6

Physicochemical Properties