HSPMdb Accession No | HSPMDB000586 |
PMID | 24265689 |
Target | Hsp70 |
HSP Name | Hsc70 |
Organism | Human |
Localization | Cytosol and nucleus |
Enzymatic activity | Inhibition of chaperone activity |
Compound Name | PES |
IUPAC Name | 2-phenylethynesulfonamide |
SMILES | C1=CC=C(C=C1)C#CS(=O)(=O)N |
% Enzymatic Inhibition/Fold Change | Significant Inhibition at 160 uM |
Site of Interaction | C-terminal domain |
Type of Enzymatic Assay | Refolding assay (luciferase) |