HSPMdb Accession NoHSPMDB000585
PMID24265689
TargetHsp70
HSP NameHsp70(1-382)
OrganismHuman
LocalizationCytosol and nucleus
Enzymatic activityInhibition of chaperone activity
Compound NamePES
IUPAC Name2-phenylethynesulfonamide
SMILESC1=CC=C(C=C1)C#CS(=O)(=O)N
% Enzymatic Inhibition/Fold ChangeSignificant Inhibition at 160 uM
Site of InteractionC-terminal domain
Type of Enzymatic AssayRefolding assay (luciferase)

Structure



HSPMDB000585

PES

Physicochemical Properties