| HSPMdb Accession No | HSPMDB000581 |
| PMID | 19195901 |
| Target | Hsp70 |
| HSP Name | PfHsp70 |
| Organism | Plasmodium falciparum |
| Localization | Cytosol and nucleus |
| Cellular activity | Antiparasitic activity (inhibition of [3H]hypoxanthine uptake) |
| Compound Name | MAL3-39 |
| IUPAC Name | benzyl 1-{3-[({[1,1'-biphenyl]-4-yl}(tert-butylcarbamoyl)methyl)[2-(morpholin-4-yl)ethyl]carbamoyl]propyl}-6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
| SMILES | CC1=C(C(NC(=O)N1CCCC(=O)N(CCN1CCOCC1)C(C(=O)NC(C)(C)C)C1=CC=C(C=C1)C1=CC=CC=C1)C1=CC=C(C=C1)[N+]([O-])=O)C(=O)OCC1=CC=CC=C1 |
| Class | Pyrimidinone amide |
| IC50 (µM) | 0.8 |
| Cellular assay | [3H]hypoxanthine uptake assay |
| Cellular Model | P. falciparum |
| Disease | Malaria |
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