HSPMdb Accession NoHSPMDB000577
PMID19195901
TargetHsp70
HSP NamePfHsp70
Organism Plasmodium falciparum
LocalizationCytosol and nucleus
Cellular activity Antiparasitic activity (inhibition of [3H]hypoxanthine uptake)
Compound NameMAL2-39
IUPAC Namebenzyl 1-butyl-4-(4-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
SMILESCCCCN1C(=O)NC(C2=CC=C(OC)C=C2)C(C(=O)OCC2=CC=CC=C2)=C1C
Class Pyrimidinone amide
IC50 (µM)0.2
Cellular assay[3H]hypoxanthine uptake assay
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB000577

MAL2-39

Physicochemical Properties