HSPMdb Accession No | HSPMDB000577 |
PMID | 19195901 |
Target | Hsp70 |
HSP Name | PfHsp70 |
Organism | Plasmodium falciparum |
Localization | Cytosol and nucleus |
Cellular activity | Antiparasitic activity (inhibition of [3H]hypoxanthine uptake) |
Compound Name | MAL2-39 |
IUPAC Name | benzyl 1-butyl-4-(4-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
SMILES | CCCCN1C(=O)NC(C2=CC=C(OC)C=C2)C(C(=O)OCC2=CC=CC=C2)=C1C |
Class | Pyrimidinone amide |
IC50 (µM) | 0.2 |
Cellular assay | [3H]hypoxanthine uptake assay |
Cellular Model | P. falciparum |
Disease | Malaria |