HSPMdb Accession No | HSPMDB000576 |
PMID | 19195901 |
Target | Hsp70 |
HSP Name | PfHsp70 |
Organism | Plasmodium falciparum |
Localization | Cytosol and nucleus |
Cellular activity | Antiparasitic activity (inhibition of [3H]hypoxanthine uptake) |
Compound Name | MAL2-29 |
IUPAC Name | 6-[5-(ethoxycarbonyl)-6-methyl-4-(3-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl]hexanoic acid |
SMILES | CCOC(=O)C1=C(C)N(CCCCCC(O)=O)C(=O)NC1C1=CC=CC(=C1)[N+]([O-])=O |
Class | Pyrimidinone amide |
IC50 (µM) | 1.6 |
Cellular assay | [3H]hypoxanthine uptake assay |
Cellular Model | P. falciparum |
Disease | Malaria |