| HSPMdb Accession No | HSPMDB000574 |
| PMID | 19195901 |
| Target | Hsp70 |
| HSP Name | PfHsp70 |
| Organism | Plasmodium falciparum |
| Localization | Cytosol and nucleus |
| Cellular activity | Antiparasitic activity (inhibition of [3H]hypoxanthine uptake) |
| Compound Name | DMT3024 |
| IUPAC Name | benzyl 1-{5-[({[1,1'-biphenyl]-4-yl}(butylcarbamoyl)methyl)[2-(morpholin-4-yl)ethyl]carbamoyl]pentyl}-6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
| SMILES | CCCCNC(=O)C(N(CCN1CCOCC1)C(=O)CCCCCN1C(=O)NC(C2=CC=C(C=C2)[N+]([O-])=O)C(C(=O)OCC2=CC=CC=C2)=C1C)C1=CC=C(C=C1)C1=CC=CC=C1 |
| Class | Pyrimidinone amide |
| IC50 (µM) | 0.2 |
| Cellular assay | [3H]hypoxanthine uptake assay |
| Cellular Model | P. falciparum |
| Disease | Malaria |
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