HSPMdb Accession NoHSPMDB000573
PMID19195901
TargetHsp70
HSP NameHsp70 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Enzymatic activityInhibition of ATPase activity
Compound NameJAB75
IUPAC Namemethyl 6-benzyl-4-(naphthalen-2-yl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
SMILESCOC(=O)C1=C(CC2=CC=CC=C2)NC(=O)NC1C1=CC2=C(C=CC=C2)C=C1
Class Pyrimidinone amide
% Enzymatic Inhibition/Fold Change0.7
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000573

JAB75

Physicochemical Properties