HSPMdb Accession No | HSPMDB000566 |
PMID | 19195901 |
Target | Hsp70 |
HSP Name | Hsp70 (HSPA1A) |
Organism | Human |
Localization | Cytosol and nucleus |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | DMT2264 |
IUPAC Name | benzyl 4-{[1,1'-biphenyl]-4-yl}-1-(5-{[(butylcarbamoyl)(cyclohexyl)methyl](hexyl)carbamoyl}pentyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
SMILES | CCCCCCN(C(C1CCCCC1)C(=O)NCCCC)C(=O)CCCCCN1C(=O)NC(C2=CC=C(C=C2)C2=CC=CC=C2)C(C(=O)OCC2=CC=CC=C2)=C1C |
Class | Pyrimidinone amide |
% Enzymatic Inhibition/Fold Change | 0.95 |
Type of Enzymatic Assay | ATPase assay |