HSPMdb Accession NoHSPMDB000553
PMID19195901
TargetHsp70
HSP NamePfHsp70
Organism Plasmodium falciparum
LocalizationCytosol and nucleus
Enzymatic activityInhibition of ATPase activity
Compound NameMAL2-215
IUPAC Namebenzyl 4-{[1,1'-biphenyl]-4-yl}-1-[5-({2-[3-(methoxycarbonyl)-2-methyl-5-phenyl-1H-pyrrol-1-yl]ethyl}carbamoyl)pentyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
SMILESCOC(=O)C1=C(C)N(CCNC(=O)CCCCCN2C(=O)NC(C3=CC=C(C=C3)C3=CC=CC=C3)C(C(=O)OCC3=CC=CC=C3)=C2C)C(=C1)C1=CC=CC=C1
Class Pyrimidinone amide
% Enzymatic Inhibition/Fold Change1.01
Type of Enzymatic AssayATPase assay
DiseaseMalaria

Structure



HSPMDB000553

MAL2-215

Physicochemical Properties