HSPMdb Accession NoHSPMDB000551
PMID19195901
TargetHsp70
HSP NamePfHsp70
Organism Plasmodium falciparum
LocalizationCytosol and nucleus
Enzymatic activityInhibition of ATPase activity
Compound NameMAL2-61
IUPAC Nameethyl 1-benzyl-6-methyl-4-{2-[(2-nitrobenzenesulfonyl)oxy]phenyl}-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
SMILESCCOC(=O)C1=C(C)N(CC2=CC=CC=C2)C(=O)NC1C1=CC=CC=C1OS(=O)(=O)C1=C(C=CC=C1)[N+]([O-])=O
Class Pyrimidinone amide
% Enzymatic Inhibition/Fold Change0.99
Type of Enzymatic AssayATPase assay
DiseaseMalaria

Structure



HSPMDB000551

MAL2-61

Physicochemical Properties