HSPMdb Accession No | HSPMDB000551 |
PMID | 19195901 |
Target | Hsp70 |
HSP Name | PfHsp70 |
Organism | Plasmodium falciparum |
Localization | Cytosol and nucleus |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | MAL2-61 |
IUPAC Name | ethyl 1-benzyl-6-methyl-4-{2-[(2-nitrobenzenesulfonyl)oxy]phenyl}-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
SMILES | CCOC(=O)C1=C(C)N(CC2=CC=CC=C2)C(=O)NC1C1=CC=CC=C1OS(=O)(=O)C1=C(C=CC=C1)[N+]([O-])=O |
Class | Pyrimidinone amide |
% Enzymatic Inhibition/Fold Change | 0.99 |
Type of Enzymatic Assay | ATPase assay |
Disease | Malaria |