HSPMdb Accession NoHSPMDB000549
PMID19195901
TargetHsp70
HSP NamePfHsp70
Organism Plasmodium falciparum
LocalizationCytosol and nucleus
Enzymatic activityInhibition of ATPase activity
Compound NameMAL2-29
IUPAC Name6-[5-(ethoxycarbonyl)-6-methyl-4-(3-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl]hexanoic acid
SMILESCCOC(=O)C1=C(C)N(CCCCCC(O)=O)C(=O)NC1C1=CC=CC(=C1)[N+]([O-])=O
Class Pyrimidinone amide
% Enzymatic Inhibition/Fold Change1.01
Type of Enzymatic AssayATPase assay
DiseaseMalaria

Structure



HSPMDB000549

MAL2-29

Physicochemical Properties