HSPMdb Accession NoHSPMDB000548
PMID19195901
TargetHsp70
HSP NamePfHsp70
Organism Plasmodium falciparum
LocalizationCytosol and nucleus
Enzymatic activityInhibition of ATPase activity
Compound NameDMT2264
IUPAC Namebenzyl 4-{[1,1'-biphenyl]-4-yl}-1-(5-{[(butylcarbamoyl)(cyclohexyl)methyl](hexyl)carbamoyl}pentyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
SMILESCCCCCCN(C(C1CCCCC1)C(=O)NCCCC)C(=O)CCCCCN1C(=O)NC(C2=CC=C(C=C2)C2=CC=CC=C2)C(C(=O)OCC2=CC=CC=C2)=C1C
Class Pyrimidinone amide
% Enzymatic Inhibition/Fold Change0.74
Type of Enzymatic AssayATPase assay
DiseaseMalaria

Structure



HSPMDB000548

DMT2264

Physicochemical Properties