HSPMdb Accession NoHSPMDB000546
PMID23607970
TargetHsp70
HSP NameSsa1-Hlj1
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound NameYM-01
IUPAC Name2-{[(2Z)-3-ethyl-5-[(2E)-3-methyl-2,3-dihydro-1,3-benzothiazol-2-ylidene]-4-oxo-1,3-thiazolidin-2-ylidene]methyl}-1-methylpyridin-1-ium chloride
SMILES[Cl-].CCN1\C(S\C(C1=O)=C1\SC2=C(C=CC=C2)N1C)=C\C1=[N+](C)C=CC=C1
ClassRhodacyanine derivative
% Enzymatic Inhibition/Fold Change10-15%
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssayATPase assay
DiseaseAlzheimers disease

Structure



HSPMDB000546

YM-01

Physicochemical Properties