HSPMdb Accession No | HSPMDB000545 |
PMID | 23607970 |
Target | Hsp70 |
HSP Name | Ssa1-Hlj1 |
Organism | Yeast |
Localization | Cytosol |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | MKT-077 |
IUPAC Name | 2-{[(2Z)-3-ethyl-5-[(2E)-3-methyl-2,3-dihydro-1,3-benzothiazol-2-ylidene]-4-oxo-1,3-thiazolidin-2-ylidene]methyl}-1-methylpyridin-1-ium chloride |
SMILES | [Cl-].CCN1\C(S\C(C1=O)=C1\SC2=C(C=CC=C2)N1C)=C\C1=[N+](C)C=CC=C1 |
Class | Rhodacyanine |
% Enzymatic Inhibition/Fold Change | 10-15% |
Site of Interaction | Nucleotide binding domain (allosteric site) |
Type of Enzymatic Assay | ATPase assay |
Disease | Alzheimers disease |