HSPMdb Accession NoHSPMDB000537
PMID23472668
TargetHsp70
HSP NameHsc70 (HSPA8)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound NameYM-07
IUPAC Name(2Z)-3-ethyl-2-[(pyridin-2-yl)methylidene]-1,3-thiazolidin-4-one
SMILESCCN1C(=O)CS\C1=C/C1=NC=CC=C1
ClassRhodacyanine derivative
EC50 (µM)>30
Site of InteractionNucleotide binding domain (allosteric site)
Cellular assayMTT viability assay
Cellular ModelMDA-MB-231
DiseaseCancer

Structure



HSPMDB000537

YM-07

Physicochemical Properties