HSPMdb Accession No | HSPMDB000536 |
PMID | 23472668 |
Target | Hsp70 |
HSP Name | Hsc70 (HSPA8) |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | YM-04 |
IUPAC Name | 2-{[(2Z)-3-ethyl-4-oxo-1,3-thiazolidin-2-ylidene]methyl}-1-methylpyridin-1-ium iodide |
SMILES | [I-].CCN1C(=O)CS\C1=C/C1=[N+](C)C=CC=C1 |
Class | Rhodacyanine derivative |
EC50 (µM) | >30 |
Site of Interaction | Nucleotide binding domain (allosteric site) |
Cellular assay | MTT viability assay |
Cellular Model | MDA-MB-231 |
Disease | Cancer |