HSPMdb Accession No | HSPMDB000530 |
PMID | 23472668 |
Target | Hsp70 |
HSP Name | Hsc70 (HSPA8) |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | YM-07 |
IUPAC Name | (2Z)-3-ethyl-2-[(pyridin-2-yl)methylidene]-1,3-thiazolidin-4-one |
SMILES | CCN1C(=O)CS\C1=C/C1=NC=CC=C1 |
Class | Rhodacyanine derivative |
EC50 (µM) | >30 |
Site of Interaction | Nucleotide binding domain (allosteric site) |
Cellular assay | MTT viability assay |
Cellular Model | MCF10A |
Disease | Cancer |