HSPMdb Accession NoHSPMDB000522
PMID23472668
TargetHsp70
HSP NameHsc70 (HSPA8)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound NameYM-04
IUPAC Name2-{[(2Z)-3-ethyl-4-oxo-1,3-thiazolidin-2-ylidene]methyl}-1-methylpyridin-1-ium iodide
SMILES[I-].CCN1C(=O)CS\C1=C/C1=[N+](C)C=CC=C1
ClassRhodacyanine derivative
EC50 (µM)>30
Site of InteractionNucleotide binding domain (allosteric site)
Cellular assayMTT viability assay
Cellular ModelMCF7
DiseaseCancer

Structure



HSPMDB000522

YM-04

Physicochemical Properties