HSPMdb Accession No | HSPMDB000521 |
PMID | 23472668 |
Target | Hsp70 |
HSP Name | Hsc70 (HSPA8) |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | YM-03 |
IUPAC Name | 3-ethyl-5-[(2E)-3-methyl-2,3-dihydro-1,3-benzothiazol-2-ylidene]-2-(methylsulfanyl)-4-oxo-4,5-dihydro-1,3-thiazol-3-ium |
SMILES | CC[N+]1=C(SC)S\C(C1=O)=C1\SC2=C(C=CC=C2)N1C |
Class | Rhodacyanine derivative |
EC50 (µM) | >30 |
Site of Interaction | Nucleotide binding domain (allosteric site) |
Cellular assay | MTT viability assay |
Cellular Model | MCF7 |
Disease | Cancer |