| HSPMdb Accession No | HSPMDB000519 |
| PMID | 23472668 |
| Target | Hsp70 |
| HSP Name | Hsc70 (HSPA8) |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Cellular activity | Antiproliferative activity |
| Compound Name | YM-08 |
| IUPAC Name | (2Z)-3-ethyl-5-[(2E)-3-methyl-2,3-dihydro-1,3-benzothiazol-2-ylidene]-2-[(pyridin-2-yl)methylidene]-1,3-thiazolidin-4-one |
| SMILES | CCN1\C(S\C(C1=O)=C1\SC2=C(C=CC=C2)N1C)=C\C1=NC=CC=C1 |
| Class | Rhodacyanine derivative |
| EC50 (µM) | 10.5 |
| Site of Interaction | Nucleotide binding domain (allosteric site) |
| Cellular assay | MTT viability assay |
| Cellular Model | MCF7 |
| Disease | Cancer |
Loading Please Wait ...