HSPMdb Accession NoHSPMDB000516
PMID23472668
TargetHsp70
HSP NameHsc70 (HSPA8)
OrganismHuman
LocalizationCytosol and nucleus
Enzymatic activityBinding affinity
Compound NameYM-07
IUPAC Name(2Z)-3-ethyl-2-[(pyridin-2-yl)methylidene]-1,3-thiazolidin-4-one
SMILESCCN1C(=O)CS\C1=C/C1=NC=CC=C1
ClassRhodacyanine derivative
IC50 (µM)5.8
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssayEnzyme-linked immunosorbent assay (ELISA)
DiseaseAlzheimers disease

Structure



HSPMDB000516

YM-07

Physicochemical Properties