HSPMdb Accession No | HSPMDB000515 |
PMID | 23472668 |
Target | Hsp70 |
HSP Name | Hsc70 (HSPA8) |
Organism | Human |
Localization | Cytosol and nucleus |
Enzymatic activity | Binding affinity |
Compound Name | YM-04 |
IUPAC Name | 2-{[(2Z)-3-ethyl-4-oxo-1,3-thiazolidin-2-ylidene]methyl}-1-methylpyridin-1-ium iodide |
SMILES | [I-].CCN1C(=O)CS\C1=C/C1=[N+](C)C=CC=C1 |
Class | Rhodacyanine derivative |
IC50 (µM) | 15 |
Site of Interaction | Nucleotide binding domain (allosteric site) |
Type of Enzymatic Assay | Enzyme-linked immunosorbent assay (ELISA) |
Disease | Alzheimers disease |