HSPMdb Accession NoHSPMDB000513
PMID23472668
TargetHsp70
HSP NameHsc70 (HSPA8)
OrganismHuman
LocalizationCytosol and nucleus
Enzymatic activityBinding affinity
Compound NameYM-02
IUPAC Name3-ethyl-5-[(2E)-3-methyl-2,3-dihydro-1,3-benzothiazol-2-ylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
SMILESCCN1C(=S)S\C(C1=O)=C1\SC2=C(C=CC=C2)N1C
ClassRhodacyanine derivative
IC50 (µM)>50
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssayEnzyme-linked immunosorbent assay (ELISA)
DiseaseAlzheimers disease

Structure



HSPMDB000513

YM-02

Physicochemical Properties