HSPMdb Accession No | HSPMDB000512 |
PMID | 23472668 |
Target | Hsp70 |
HSP Name | Hsc70 (HSPA8) |
Organism | Human |
Localization | Cytosol and nucleus |
Enzymatic activity | Binding affinity |
Compound Name | YM-08 |
IUPAC Name | (2Z)-3-ethyl-5-[(2E)-3-methyl-2,3-dihydro-1,3-benzothiazol-2-ylidene]-2-[(pyridin-2-yl)methylidene]-1,3-thiazolidin-4-one |
SMILES | CCN1\C(S\C(C1=O)=C1\SC2=C(C=CC=C2)N1C)=C\C1=NC=CC=C1 |
Class | Rhodacyanine derivative |
IC50 (µM) | 0.61 |
Site of Interaction | Nucleotide binding domain (allosteric site) |
Type of Enzymatic Assay | Enzyme-linked immunosorbent assay (ELISA) |
Disease | Alzheimers disease |