HSPMdb Accession NoHSPMDB000512
PMID23472668
TargetHsp70
HSP NameHsc70 (HSPA8)
OrganismHuman
LocalizationCytosol and nucleus
Enzymatic activityBinding affinity
Compound NameYM-08
IUPAC Name(2Z)-3-ethyl-5-[(2E)-3-methyl-2,3-dihydro-1,3-benzothiazol-2-ylidene]-2-[(pyridin-2-yl)methylidene]-1,3-thiazolidin-4-one
SMILESCCN1\C(S\C(C1=O)=C1\SC2=C(C=CC=C2)N1C)=C\C1=NC=CC=C1
ClassRhodacyanine derivative
IC50 (µM)0.61
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssayEnzyme-linked immunosorbent assay (ELISA)
DiseaseAlzheimers disease

Structure



HSPMDB000512

YM-08

Physicochemical Properties