HSPMdb Accession NoHSPMDB000501
PMID26839186
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol and nucleus
Enzymatic activityInhibition of chaperone activity
Compound Namealkylamino-substituted acridizinium derivative 2
IUPAC Name9-(pyrrolidin-1-yl)-5??-pyrido[1,2-b]isoquinolin-5-ylium bromide
SMILES[Br-].C1CCN(C1)C1=CC2=CC3=CC=CC=[N+]3C=C2C=C1
Class9-aminoacridizinium derivative
IC50 (µM)127
Type of Enzymatic AssayRefolding assay (luciferase)

Structure



HSPMDB000501

alkylamino-substituted acridizinium derivative 2

Physicochemical Properties