HSPMdb Accession No | HSPMDB000498 |
PMID | 25500222 |
Target | Hsp70 |
HSP Name | Hsp70i |
Organism | Human |
Localization | Cell surface |
Enzymatic activity | Inhibition of ATP binding |
Cellular activity | Inhibition of tumor growth |
Compound Name | HS-72 |
IUPAC Name | ((S)-N-(1-propyl-1Hbenzo[d]imidazol-2-yl)-1-(pyrazin-2-yl)piperidine-3-carboxamide) |
SMILES | CCCn1c(NC(=O)[C@H]2CCCN(C2)c3cnccn3)nc4ccccc14 |
Class | Purine analogue |
Site of Interaction | Allosteric site |
Type of Enzymatic Assay | Fluorescence linked enzyme chemoproteomic strategy (FLECS) |
HSP client protein assay | Her2 degradation assay |
Cellular Model | HeLa |
Disease | Cancer |