| HSPMdb Accession No | HSPMDB000494 |
| PMID | 29953808 |
| Target | Hsp70 |
| HSP Name | Hsp70 |
| Organism | Human |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of HSP 70 BAG interaction |
| Compound Name | JG-294 |
| IUPAC Name | 2-((Z)-((E)-5-(6-bromo-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-ethyl-4-oxothiazolidin-2-ylidene)methyl)-3-((5-(trifluoromethyl)furan-2-yl)methyl)thiazol-3-ium chloride |
| SMILES | [Cl-].CCN\1C(=O)/C(SC1=C\c2scc[n+]2Cc3oc(cc3)C(F)(F)F)=C/4Sc5cc(Br)ccc5N4C |
| Class | Benzothiazole Rhodacyanines derivative |
| Ki (µM) | 0.35 |
| Site of Interaction | Allosteric site |
| Type of Enzymatic Assay | Hsp70-BAG interaction assay |
| Disease | Cancer |
Loading Please Wait ...