| HSPMdb Accession No | HSPMDB000493 |
| PMID | 29953808 |
| Target | Hsp70 |
| HSP Name | Hsp70 |
| Organism | Human |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of HSP 70 BAG interaction |
| Compound Name | JG-231 |
| IUPAC Name | 3-((5-bromothiophen-2-yl)methyl)-2-((Z)-((E)-5-(6-chloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-ethyl-4-oxothiazolidin-2-ylidene)methyl)thiazol-3-ium chloride |
| SMILES | [Cl-].CCN1C(=O)C(\S\C1=C/c2scc[n+]2Cc3sc(Br)cc3)=C4/Sc5cc(Cl)ccc5N4C |
| Class | Benzothiazole Rhodacyanines derivative |
| Ki (µM) | 0.11 |
| Site of Interaction | Allosteric site |
| Type of Enzymatic Assay | Hsp70-BAG interaction assay |
| Disease | Cancer |
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