HSPMdb Accession NoHSPMDB000486
PMID20012863
TargetHsp70
HSP NameHsc70 (HSPA8) and Hsp70 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound NameVER-82160
IUPAC Name2-amino-4-{2,4-dichloro-5-[2-(diethylamino)ethoxy]phenyl}-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide
SMILESCCNC(=O)C1=CC2=C(S1)N=C(N)N=C2C1=C(Cl)C=C(Cl)C(OCCN(CC)CC)=C1
Class Dibenzyl-8-amino adenosine analogue
GI50 (µM)0.123
Cellular assayCell cycle analysis
Cellular ModelMDA-MB-468

Structure



HSPMDB000486

VER-82160

Physicochemical Properties