HSPMdb Accession No | HSPMDB000484 |
PMID | 20012863 |
Target | Hsp70 |
HSP Name | Hsp70 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Antiproliferative activity |
Compound Name | VER-155008 |
IUPAC Name | 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethyl]benzonitrile |
SMILES | C1=CC(=CC=C1COCC2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3NCC5=CC(=C(C=C5)Cl)Cl)O)O)C#N |
Class | Dibenzyl-8-amino adenosine analogue |
GI50 (µM) | 12.8 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Cell cycle analysis |
Cellular Model | HT29 |