HSPMdb Accession NoHSPMDB000481
PMID20012863
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol
Cellular activityAntiproliferative activity
Compound NameVER-155008
IUPAC Name4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethyl]benzonitrile
SMILESC1=CC(=CC=C1COCC2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3NCC5=CC(=C(C=C5)Cl)Cl)O)O)C#N
Class Dibenzyl-8-amino adenosine analogue
GI50 (µM)10.4
Site of InteractionNucleotide binding domain
Cellular assayCell cycle analysis
Cellular ModelBT474

Structure



HSPMDB000481

VER-155008

Physicochemical Properties