HSPMdb Accession NoHSPMDB000469
PMID19256508
TargetHsp70
HSP NameHsc70
OrganismHuman
LocalizationCytosol
Cellular activityAntiproliferative activity
Compound Name10
IUPAC Name(2R,3R,4S,5R)-2-[6-Amino-8-(3,4-dichlorobenzylamino)-purin-9-yl]-5-methoxymethyltetrahydrofuran-3,4-diol
SMILESCOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2c(NCc3ccc(Cl)c(Cl)c3)nc4c(N)ncnc24
ClassAdenosine derivative
GI50 (µM)>80
Site of InteractionNucleotide binding domain
Cellular assayMTT viability assay
Cellular ModelHCT116

Structure



HSPMDB000469

10

Physicochemical Properties