HSPMdb Accession No | HSPMDB000469 |
PMID | 19256508 |
Target | Hsp70 |
HSP Name | Hsc70 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Antiproliferative activity |
Compound Name | 10 |
IUPAC Name | (2R,3R,4S,5R)-2-[6-Amino-8-(3,4-dichlorobenzylamino)-purin-9-yl]-5-methoxymethyltetrahydrofuran-3,4-diol |
SMILES | COC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2c(NCc3ccc(Cl)c(Cl)c3)nc4c(N)ncnc24 |
Class | Adenosine derivative |
GI50 (µM) | >80 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | MTT viability assay |
Cellular Model | HCT116 |